The Archive

Previous editions of BioBucks

Daily biotech dealflow and market tape

September 2026

08
Tuesday: Novartis drops 10% on its 2nd Phase 3 flop
Novo scraps two more ziltivekimab trials, and FDA approves a drug off a blood test.
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04
Friday: Ionis lands a first, GSK pays $110M for a pre-IND molecule
An ultra-rare approval, a 74% response rate, and a licence signed before Phase 1.
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03
Thursday: Ultragenyx drops 44% after the bell
A clean Phase 3 miss, an FDA warning shot, and $3.22B for a better needle.
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02
Wednesday: Novartis wins in MS, Alumis drops 54%
Two Phase 3 wins for a BTK pill, and Roche writes another China check.
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01
Tuesday: 3 deaths freeze CAR-T, 9 more names sign MFN
Class-wide safety scare, a 26-name pricing club, and ARCH goes shopping for $3B.
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August 2026

31
Monday: Lilly drops $2.9B on Merida as Wainua stumbles in Munich
ESC hands out a split verdict; Takeda's $275M cheque clears on the way.
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28
Friday: Roivant's first, Gilead's third, Genentech's $45M
Roivant finally has something to sell, and Genentech pays up for the payload after next.
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27
Thursday: FDA clears Revolution Medicines' Rasonque 6.5 months early
Revolution's review clock ran fast, Biohaven's ran out of patience at $795M.
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26
Wednesday: ARCH's $1.5B China NewCo and Jazz's 26.4-month OS
Plus: Zymeworks banks $250M and falls 7%. Bristol Myers walks.
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25
Tuesday: Merck's 3rd IRA loss and a 23% gene therapy gut-punch
Alzheimer's gets a blood test, Regenxbio gets five bad MRIs, Munich opens Friday.
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24
Monday: Roche pays $190M up front to keep the muscle on
Non-incretin obesity, a GOP letter aimed at China trial data, and Capricor’s PDUFA comes and goes.
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21
Friday: BMS rents AI models, Amgen walks from $500M in milestones
Roche commits $750M to a plant that won't fill a syringe until 2031.
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20
Thursday: Moderna's 177% day and two first-ever approvals
Moderna adds $44B of market cap in a session, and the FDA hands out two firsts.
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19
Wednesday: Trump's FDA pick and BioMarin's $275M bone bet
Overton heads for a Senate fight, and a third China trial death surfaces.
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18
Tuesday: EyePoint's 70% wipeout hits wet AMD
Duravyu's primary miss, a PD-1/VEGF curve that shrank, and AstraZeneca finally printing a win.
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17
Monday: AstraZeneca's 895-patient bispecific bet folds
Capricor doubles on an FDA reprieve, and Redx backs into Nasdaq with $125M.
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14
Friday: BMS lands the first CELMoD at $29,500 a cycle
Zipalertinib clears Phase 3, and the FDA puts a price on where you run Phase 1.
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13
Thursday: Definium's LSD pill goes 2-for-2 in Phase 3
Plus: PTC raids the Sangamo estate for $111M, and Vykat XR draws heat.
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12
Wednesday: Zydus options a $475M shot at alpha-1
Three drugmakers take Illinois to court, and crossover money backs an FSHD editor.
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11
Tuesday: Jazz pays $820M upfront for Actio
Jazz swings for rare epilepsy, Trump targets childhood shots, and Sionna hands Vertex a free pass.
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10
Monday: DC drafts brakes on $136B of China deal flow
Grail's failed test finally gets a date with an FDA panel.
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07
Friday: Latigo prices $345.6M, Replimune clears the FDA
Two rejections, one adcomm, one approval — plus $450M for a drug that reads out in 2029.
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06
Thursday: A $400B merger dies, 2 FDA nods land
Reuters says the AstraZeneca-Bristol Myers talks are off. Also: two IPOs price.
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05
Wednesday: PrEP clears $1B, KKR clears $5.7B
Hinge expands into digestive care, Gilead's Yeztugo beats, and Merck leans harder into the Keytruda combo play.
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04
Tuesday: Curium's $8B bid for the PSMA scan business
Curium takes Lantheus private, Pathos writes a $125M check, and Jazz raises the year.
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